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He will finally get his chance to run out in the side, potentially alongside long-time friend Liberatore, who has also been named on the bench.

"There is one player a definite out at this stage, which is Daniel Giansiracusa. He's out with a hamstring injury, which he unfortunately hurt during training," Eade told westernbulldogs.com.au on Thursday.

"I can confirm at this stage that Mitch will make his debut and he will be in the final 22. So he'll be going to Perth with us and we'll take another player as well, as the final 23," he said.

On Wednesday, Eade said last weekend's bye meant Liberatore was likely to play against Fremantle after his young body benefitted from a rest. 

"We won't [rest him] now because he's had the week off last week," he said after training.

"We'll just monitor that as we go along and see how his fatigue levels are but there's no doubt young players will find it tougher.

"The fatigue levels will come quicker for them and that's what we've got to monitor with Tom."

Ruckman Will Minson has also been named on the extended bench for his first game for the season, along with Lindsay Gilbee, who played VFL last weekend to boost his match fitness after overcoming a hamstring strain, and Dylan Addison, who could play his first game for the year after he missed round one with suspension.

Tom Williams and Daniel Cross have been named despite the former pulling out of training on Wednesday with back spasms and the latter missing the session with illness.

Eade also said the Dogs were primed for the match after managing their 16-day break between rounds three and five with a careful mixture of recovery and training.

"Week one was spent on recovery. The last week we've been ramping up and are looking forward to our Anzac Day game," he said.

"We're sitting two [wins] and one [loss] after three games and are now heading into a very tough period. We're looking forward to Monday in a big way."